Dictyoceratin
WebMar 1, 2015 · Total syntheses of (+)-dictyoceratin-C (1) and (+)-dictyoceratin-A (smenospondiol) (2), hypoxia-selective growth inhibitors isolated from marine sponge, … Webdictyoceratin-C (1) &HtH Dictyoceratin-C (1)lùN I 30 o) dictyoceratin-A (2)ñÈN 1 (Figure DU 145 100 o MeO 17 OH 18 R = H dictyoceratin-C (1) OH dictyoceratin-A (2) Figure 1 o hypoxia OX i a 80 60 40 20 10 30 concentration of 1 (PM) Structural optimization and mechanistic analysis of the anti-proliferative
Dictyoceratin
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WebMar 8, 2024 · Hypoxia-adapted cancer cells in tumors contribute to the pathological progression of cancer. The marine spongean sesquiterpene phenols dictyoceratin-A (1) … http://www.earlychristianwritings.com/diatessaron.html
WebDOI: 10.1016/S0040-4020(01)87643-2 Corpus ID: 92510326; Dictyoceratin-A and -B, Novel Antimicrobial Terpenoids from the Okinawan Marine Sponge sp. @article{Nakamura1986DictyoceratinAA, title={Dictyoceratin-A and -B, Novel Antimicrobial Terpenoids from the Okinawan Marine Sponge sp.}, author={Hideshi Nakamura and … WebDec 16, 2015 · Oral dictyoceratin-C (1) and A (2), hypoxia-selective growth inhibitors, showed potent in vivo antitumor effects in mice subcutaneously inoculated with sarcoma S180 cells. Structurally modified analogs were …
WebJul 1, 2015 · Dictyoceratin-C (1) inhibited proliferation of human prostate cancer DU145 cells selectively under hypoxic condition in a dose-dependent manner at the concentrations ranging from 1.0 to 10 μM. The subsequent structure–activity relationship study using nine sesquiterpene phenol/quinones ( 2 – 10 ), which were isolated from marine sponge ... WebFeb 1, 2024 · Screening of the extract library revealed that the extract of the marine sponge Dactylospongia metachromia inhibited cell cycle progression at S/G2/M phases. Bioassay-guided fractionation afforded a new sesquiterpene quinone, neoisosmenospongine (1), and four known compounds, nakijiquinone I, N, and Q (2-4) and (-)-dictyoceratin-C (5).
WebDownload scientific diagram Chemical structures of dictyoceratin-A (1) and-C (2) and their probes (3-5). from publication: Target Identification of the Marine Natural Products Dictyoceratin-A ...
WebOral dictyoceratin-C (1) and A (2), hypoxia-selective growth inhibitors, showed potent in vivo antitumor effects in mice subcutaneously inoculated with sarcoma S180 cells. ear infection with vertigoWebKeywords: dictyoceratin-A; hypoxia; cancer; RNA polymerase II-associated protein 3; probe molecule; target molecule 1. Introduction In tumors, the hypoxic environment is an important factor for tumor growth, angiogenesis, metastasis, and response to chemotherapy and irradiation. Tumor cells in the hypoxic environment css element with class selectorWebDec 16, 2015 · Oral dictyoceratin-C (1) and A (2), hypoxia-selective growth inhibitors, showed potent in vivo antitumor effects in mice subcutaneously inoculated with sarcoma … cs-selfserveWebDec 16, 2015 · Abstract: Oral dictyoceratin-C (1) and A (2), hypoxia-selective growth inhibitors, showed potent in vivo antitumor effects in mice subcutaneously inoculated with sarcoma S180 cells. Structurally modified analogs were synthesized to assess the structure–activity relationship of the natural compounds 1 and 2 isolated from a marine … css ellipsis two linesWebApr 1, 2024 · Using various chromatographic methods, five new sesquiterpene derivatives named smenohaimiens A-E (1-5) and five known, 19-hydroxy-polyfibrospongol B (6), ilimaquinone (7), dictyoceratin C (8), polyfibrospongol A (9), and polyfibrospongol B (10) were isolated from the marine sponge Smenospongia cerebriformis Duchassaing & … css eliteroyalWebDec 16, 2015 · Oral dictyoceratin-C (1) and A (2), hypoxia-selective growth inhibitors, showed potent in vivo antitumor effects in mice subcutaneously inoculated with sarcoma S180 cells. Structurally modified analogs were synthesized to assess the structure-activity relationship of the natural compounds 1 and 2 isolated from a marine sponge. ear infection with pus in adultsWebJan 1, 1986 · Two new antimicrobial sesquiterpenoids, dictyoceratin-A (3a) and -B (4a) were isolated from the Okinawan marine sponge Hippospongia sp. along with known … css embed